Diagnostic Service

Risk of Ovarian Malignancy Algorithm (ROMA)

A comprehensive baseline diagnostic profile to check your core health markers — for safety, confidence, and smarter treatment decisions.

5 working daysTurnaround
🕐10mDuration
🧪BloodSample Required
✓ Cancer Antigen 125 (CA 125), Human Epididymis Protein 4 (HE4), ROMA ✓ PRE, ROMA ✓ POST
£ 110,00
Risk of Ovarian Malignancy Algorithm (ROMA)
About This Service

What is the Risk of Ovarian Malignancy Algorithm (ROMA)?

The Risk of Ovarian Malignancy Algorithm (ROMA) is a specialized blood test designed to assess the likelihood of ovarian cancer in women. By analyzing specific tumor markers, this profile provides a comprehensive risk evaluation, helping healthcare providers differentiate between benign and malignant ovarian conditions. The ROMA test combines levels of Cancer Antigen 125 (CA 125) and Human Epididymis Protein 4 (HE4) with patient menopausal status (ROMA-PRE for premenopausal and ROMA-POST for postmenopausal women), offering a highly accurate prediction of ovarian malignancy risk. Indications for testing The ROMA test is indicated for women who present with symptoms suggestive of ovarian cancer, such as persistent bloating, pelvic pain, abnormal menstruation, or a noticeable mass in the pelvic area. It is also recommended for women with a family history of ovarian or breast cancer, as well as those undergoing routine monitoring for known ovarian cysts or other gynecological abnormalities. What can be detected? The Risk of Ovarian Malignancy Algorithm (ROMA) helps to: Evaluate ovarian cancer risk: By measuring CA 125 and HE4, the ROMA test assesses the likelihood of ovarian malignancy, providing valuable guidance for further diagnostic procedures such as imaging or biopsy. Differentiate between benign and malignant conditions: ROMA helps healthcare providers distinguish between non-cancerous ovarian cysts and those that may require urgent intervention, aiding in the decision-making process. Monitor treatment response: In women with diagnosed ovarian cancer, this test can help track disease progression and response to treatment, allowing for adjustments in care as needed. Who is this test for? The ROMA test is particularly useful for women at high risk of ovarian cancer due to symptoms, family history, or existing ovarian abnormalities. It is also valuable for women undergoing evaluation for pelvic masses or who are being monitored for recurrence after treatment for ovarian cancer. Fasting requirements No fasting is required for the ROMA test. However, it is important to follow any specific instructions provided by your healthcare provider to ensure accurate results.
This service is for you if…
  • 1You want clear, objective information about your health — not guesswork
  • 2You are starting a new treatment, therapy, or wellness programme and want a safe baseline
  • 3You have ongoing symptoms that haven't been explained by a GP visit
  • 4You want to monitor your progress after lifestyle, dietary, or medical changes
  • 5You prefer to be proactive about your health rather than reactive
Why This Service

Why do you need this?

Many issues only become obvious after they have already affected your quality of life. This service gives you actionable data early — so you can make informed decisions rather than waiting for symptoms to worsen.

Whether you are maintaining good health or investigating a specific concern, having an accurate baseline changes what steps you take next.

Common reasons people book
  • Persistent fatigue or unexplained low energy
  • Preparing for a new treatment or aesthetic procedure
  • Annual health review — private, fast, and thorough
  • Investigating symptoms their GP hasn't fully explored
  • Wanting a second opinion backed by lab data
Simple Process

How it works

From booking to results in three straightforward steps.

1

Book Online

Choose your test, select a clinic or home visit, and confirm your appointment in seconds.

2

Visit Our Clinic

Attend one of our accredited clinics at your chosen time. Our team will carry out the sample collection quickly and comfortably.

3

Get Your Results

Your sample is analysed by accredited labs. Secure results delivered in 2–3 working days.

Understanding Your Report

Your results explained

Your report presents each marker clearly against established reference ranges — making it straightforward to understand where you stand and what, if anything, needs attention.

Low

Below Range

A result below the reference range means a marker is lower than expected. This can affect how you feel and may need dietary, supplementation, or clinical attention.

Next step: Review with a clinician to determine whether correction is needed.
Balanced

Within Range

Results within the expected range indicate this marker is functioning normally. A good baseline for any planned treatment or lifestyle programme.

Next step: Proceed with confidence, and retest periodically to track changes.
Elevated

Above Range

A result above the reference range may indicate physiological stress or an imbalance that deserves attention — even before any symptoms are present.

Next step: Clinician review is recommended before proceeding with any treatment.
How to read your report
Each marker is shown with its result alongside the lab's reference rangeClear
Out-of-range results are flagged with Low (L) or High (H) indicatorsFlagged
Results are compared to UK lab reference standardsUK Standard
Report delivered securely by email or patient portalPrivate
Follow-up consultation available if requiredSupported
Before Your Appointment

How to prepare

🕐

Sample Timing

Attend between 7am and 12pm where possible. Wait until any illness has fully resolved. Avoid intense exercise for 24–48 hours beforehand, as this can affect certain markers.

💧

Fasting & Hydration

Fasting is not always required, but some tests may recommend it. If fasting is advised, avoid food for 8–12 hours and drink water only. Stay well hydrated for accurate sample collection.

💊

Medications & Supplements

Continue prescribed medications unless advised otherwise. Avoid vitamin, mineral, or biotin supplements for at least 24–48 hours before your test, as these can interfere with results.

🌸

Hormones & Menstrual Cycle

For hormone-related tests, timing within your menstrual cycle may be important. Follow the specific guidance provided in your booking confirmation email.

Registered & Accredited With UK Health Authorities

FAQ

Frequently asked questions

This service is designed to give you a clear and accurate picture of the relevant health markers — presented in a structured report with reference ranges so you know exactly where you stand.
No. You can book directly without a referral. Our services are available to adults seeking private diagnostic or assessment appointments.
The appointment takes approximately 10m. You will be advised of any specific preparation requirements when you book.
Results are typically ready within 5 working days. You will receive them securely by email or through your patient portal, with clear reference ranges included.
Yes. For applicable services, a certified clinician or phlebotomist can attend your home, workplace, or hotel. Select the home visit option when booking.
You will receive a clearly formatted report. If any result is flagged outside the normal range, we recommend reviewing it with your GP or a specialist. Many findings are straightforward to address once identified.
Yes. You can book on behalf of a family member or partner. Simply provide their details at the time of booking and ensure they bring valid ID to the appointment.
UKAS ACCREDITED LABS
Same-Day
Results

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